8 NOV 2018

*Programme subject to change

08:45 - Delegate Registration, Expo & Surgeries

Exhibition takes place in Foyer and Exeter 2

09:30 - Conference Chair Introduction

Speaker: Doris-Ann Williams MBE, Chief Executive, BIVDA

09:40 - Keynote Address - UK AMR Diagnostics Collaborative

Speaker: Fiona Carragher, Deputy Chief Scientific Officer, NHS England

9.50 - How diagnostics can drive efficiency within the NHS

Speaker: Professor Adrian Newland CBE, Professor of Haematology, Barts and the London School of Medicine and Dentistry

10.05 – Using Pathology networks to drive efficient patient care

Speaker: David Wells, Head of Pathology Services Consolidation, NHS Improvements

10:20 - A partnered development of a circulating tumour ESR1 Mutation Test for the detection of metastatic breast cancer mutations indicative of resistance to endocrine hormone therapy

Speaker: Ciaran Fulton, Head of Diagnostics, Centre for Diagnostics Development (CDD), LifeArc

10:35 - Smartphone-enabled point of care testing - transforming the way we approach diagnosis and treatment

Speaker: Dr Neil Polwart, Novarum Founder, BBI Group Head of Mobile

As mobile technology has an ever increasing impact on our lives the permeation of mobile technology into diagnosis and treatment of disease is almost inevitable.Whilst there are many ways to envisage point of care tests integrating with mobile phones, we will describe our patent protected approach to detecting, analysing and interpreting low cost simple to use diagnostic devices for use outside traditional clinical laboratories.

In addition to describing case studies for projects covering a range of applications including infectious disease and monitoring chronic conditions, we will outline a vision for how smartphone connected point of care testing can be used to introduce improved antimicrobial stewardship.

10:50 - Panel Debate- How do we create a diagnostic pathway for the UK

Chair: Daniel Berman, Longitude Prize, Challenge Prize Centre, Nesta

Panelist: Doris-Ann Williams, Chief Executive, BIVDA

Panelist: Fiona Carragher, Deputy Chief Scientific Officer, NHS England

Panelist: Professor Adrian Newland CBE, Professor of Haematology, Barts and the London School of Medicine and Dentistry

Panelist: David Wells, Head of Pathology Services Consolidation, NHS Improvements

11:30 - Refreshments, Expo & Surgeries

11:50 - Diagnostics in action- Workshop Breakout session 1-

Delegates choose 1 stream from each workshop session

Essex Suite- Stream 1 - Improvement in the quality and reproducibility of diagnostic assays

This presentation will address the application of reference materials measuring quality linked to a primary physical reference “the International Standard”, wherever possible, can provide assurance of the quality of the data and, in turn, support improved clinical management of patients.

Speaker: Clare Morris, Senior Scientist, NIBSC

Exeter 1-Stream 2 - Improving clinician confidence and decision making in the management of patients over 65 presenting with acute frailty syndromes-

As sponsored by Abbott

This presentation will address a project which with the addition of a diagnostic tool facilitated improved decision making, earlier identification of illness and better patient management.

Speaker: Melinda McPherson, Trainee Advanced Clinical Practitioner, South central Ambulance Service

12.30- Diagnostics in action- Workshop Breakout session 2

Exeter 1-Stream 3- BiomArker-guided Duration of Antibiotic treatment in hospitalised PaTients with suspected Sepsis: the ADAPT-Sepsis Trial

This presentation will explore a recent UK-wide multi-centre randomised controlled trial to determine whether a treatment protocol based on monitoring CRP or PCT safely allow a reduction in duration of antibiotic therapy in hospitalised adult patients with suspected sepsis

Speaker: Professor Paul Dark, Chair of Critical Care Medicine, Manchester University NHS Foundation Trust and Northern NHS Care Alliance

Essex suite-Stream 4 -Real-world evaluation and implementation of a diagnostic test for pre-eclampsia

Pre-eclampsia (PE) is a multisystem hypertensive disorder that affects 3-5% of all pregnancies. The disease is a serious cause of maternal and foetal morbidity in the UK and clinical teams therefore have a high degree of suspicion for the disease and a low threshold for admitting pregnant women with suspected PE

Oxford AHSN has been leading a project with Roche Diagnostics and clinicians in the Oxford AHSN region to evaluate and implement the Elecsys® test as part of a new clinical pathway to reduce patient risk in maternity units. This workshop highlights the challenges and benefits of introducing a new clinical pathway and the importance of conducting a robust real world evaluation to facilitate implementation.

Speakers: Julie Hart & Guy Checketts, Oxford AHSN

13.10 - Lunch, Expo,Poster Session & Surgeries

Overcoming the challenges and progressing the Diagnostics landscape

14:00 - In-Vitro diagnostic regulations, challenges and opportunities in a post-Brexit UK

Speaker: Alison Dennis, Partner, Fieldfisher

14:15 - CASE STUDY in diagnostic test research: the i-sense EPSRC IRC in Early Warning Sensing Systems for Infectious Diseases

Speaker: Rachel McKendry, Professor, Biomedical Nanotechnology, London Centre for Nanotechnology, UK

14:35 -CASE STUDY: CRP in Community Pharmacies

A recent study conducted in UK and estimated an 80% reduction in antibiotic Rx and also significantly reduced the attendance at GPs surgery. These two factors make community pharmacy a cost effective site for POC CRP testing. As a result, the intervention has been included in NHS England grant to extend the service to more pharmacies already engaged in providing access to medication for the treatment of ear, nose, throat (ENT) conditions and for bacterial conjunctivitis which is due to start this coming flu season. In addition it is planned to educate all members of the community-GP surgeries, schools, community groups etc in the town where the first trial was conducted to create a fully integrated POC CRP testing service in which all of the community are engaged.

Speaker: Mike Wakeman, Pharmacist & Healthcare Consultant

14:55 -CASE STUDY: Making the business case for Diagnostics within your organisation

As sponsored by Abbott

Oldham has issues with higher levels of antibiotic prescribing than most other Greater Manchester CCGs. Oldham has the 2nd highest weighted prescribing of antibacterial. QIPP indicator (Quality, Innovation, Productivity and Prevention) showed 22 Oldham practices in the bottom national quartile. Oldham Antimicrobial policy developed in 2013 in collaboration with North East sector to provide guidance to GPs about appropriate antibiotic prescribing on commonly presented infections. This failed to reduce the prescribing. In this presentation Anita Sharma will discuss how she gained funding support to tackle these high levels and her findings.

Speaker: Dr Anita Sharma,GPwSI Gynaecology, Clinical Lead Oldham GP Federation

15:15 - Closing Keynote- How Diagnostics make economic sense for the NHS

Lord O'Neill will present on the economic benefits brought to the UK Economy by utilising Diagnostics within our health service. Jim will address how Diagnostics is the single most important intervention in tackling Antimicrobial Resistance

Speaker: Lord Jim O'Neill of Gatley

15:35 - Chair closing remarks

15:40 - Conference Close

Check back soon for the 2018 conference. You can view slides from our 2017 conference by clicking the button below.